Dr. Natalie Crawford is a double board-certified reproductive endocrinologist and fertility doctor, based in Austin, Texas. She’s also the author of the brand new book, The Fertility Formula, which comes out on April 14th.

Nicole LePera, Ph.D., is the creator of the worldwide @theholisticpsychologist movement, and the author of multiple bestselling books including How to Do the Work and her newest, Reparenting the Inner Child. She was trained in clinical psychology at Cornell University and the New School for Social Research and studied at the Philadelphia School of Psychoanalysis. Her work has reached tens of millions of people on social media, who are waking up to the idea that healing doesn't happen in a therapist's office alone.

Bill Gifford, a veteran science journalist and author of Spring Chicken, a New York Times bestseller on longevity. His latest book, Hotwired: How the Hidden Power of Heat Makes Us Stronger, dives deep into the emerging science of heat, sweating, and what happens when we stop running from discomfort.

Deepika Chopra, Ph.D. (widely known as The Optimism Doctor) is a clinical health psychologist, visual imagery expert, and author of the upcoming book The Power of Real Optimism. But here's what makes Deepika's work so different: she's not selling you positivity. In this episode, we get into the real science of optimism—and why it has far more to do with resilience and curiosity than with good vibes.

Victoria Maizes, M.D., is the Executive Director of the Andrew Weil Center for Integrative Medicine and co-host of the Body of Wonder podcast. She's a leading voice in integrative medicine and author of the new book Heal Faster, which makes the case that modern medicine has been so focused on treating disease that it's largely overlooked the body's most powerful asset: its innate capacity to heal.

Today's guest is Majid Fotuhi, M.D., a Harvard and Johns Hopkins-trained neurologist, brain health researcher, and author of Invincible Brain. Dr. Fotuhi has spent his career studying one of the most pressing questions of our time: why do some people's brains deteriorate with age, while others stay sharp well into their eighties and nineties? His answer might surprise you.

Coyle is the bestselling author of The Culture Code and The Talent Code, who just released his latest book, Flourish: The Art of Building Meaning, Joy, and Fulfillment. After spending decades studying elite performers, Navy SEALs, championship sports teams, and top business leaders, Coyle had climbed to the mountaintop of success research only to realize it wasn’t what he thought it would be. Now, he focuses his work trying to answer the question: What actually makes a life worth living? 

Sahil Bloom is a NYT bestselling author of The 5 Types of Wealth: A Transformative Guide to Design Your Dream Life. He’s also an entrepreneur, investor and a proud, son, husband, and father who believes the greatest things in life come not from finding the right answers, but from asking the right questions.

Elizabeth Yurth, M.D., a double board-certified physician in Physical Medicine & Rehabilitation and Anti-Aging/Regenerative Medicine, joins us on the podcast to discuss why peptides are much more than an Instagram trend, what forms of peptides might be most beneficial, and how to be mindful of safety and quality if you’re trying to incorporate them into your own protocol.

Gabrielle Lyon, D.O., a fellowship-trained physician, a bestselling author, and a pioneer of muscle-centric medicine, joins us today to dive into the science of muscle as the organ of longevity, from resistance training and protein intake to building strength that lasts.

In this deeply personal solo episode, mindbodygreen co-founder and co-CEO Jason Wachob shares his N-of-1 longevity experiment—and all the data behind it. At 51 years old, Jason’s biological age clocks in at 37.9, with elite cardiovascular and recovery metrics to match: a VO₂ max of 52, resting heart rate as low as 35, and record-high HRV.

Tara Narula, M.D., a board-certified cardiologist, Assistant Professor of Cardiovascular Medicine, and author of The Healing Power of Resilience, joins us today to explore how resilience, stress, and mindset profoundly shape heart health—and how we can build these skills to improve both recovery and long-term wellbeing.

Maya Shankar, Ph.D., a cognitive scientist, creator and host of the award-winning podcast A Slight Change of Plans, and author, joins us today to explore what science and lived experience reveal about navigating life's most difficult transitions, and how unexpected change can become a powerful form of revelation.

Saranya Wyles, M.D., Ph.D., a dermatologist, regenerative medicine scientist, and the director of the Regenerative Dermatology & Skin Longevity Lab at the Mayo Clinic, joins us today to unpack how the skin reflects systemic aging and the emerging therapies shaping the future of regenerative dermatology.

Here’s the story of some scientists in the 1980s who tried to cause heart disease in rabbits. Instead, they stumbled upon a discovery so surprising it challenged everything we thought we knew about cardiovascular health—and may hold a powerful lesson for human longevity.

Jaime Seeman, M.D., a board-certified Obstetrician-Gynecologist and member of mindbodygreen’s scientific board of advisors, joins us today to dive deep into how women can support muscle, hormones, and metabolic health across every decade of life.

Rocío Salas-Whalen, M.D., a board-certified Endocrinologist, Obesity Medicine specialist, and widely recognized as one of the earliest adopters of GLP-1 therapies in the United States, joins us today to explain how GLP-1s work, who truly benefits, and the crucial steps you need to take to protect your metabolism along the way.

David Fajgenbaum, M.D., physician-scientist, bestselling author of Chasing My Cure, co-founder of Every Cure, and leader in the global push for drug repurposing, joins us today to explain why the cures of tomorrow may already be on pharmacy shelves today—and how his team is racing to uncover them.

Ana Kausel, M.D., a board-certified endocrinologist and women’s health expert, joins us today to share how women can build metabolic strength from the inside out—through muscle, nutrition, hormones, and lifestyle.

Shannon Ritchey, P.T., DPT, , Doctor of Physical Therapy, personal trainer, and the founder of Evlo Fitness, joins us today to share how you can train smarter—not harder—to build strength, protect your body, and finally see results that last.

Daniel Amen, M.D., a physician, double board-certified psychiatrist, award-winning researcher, and 20-time national bestselling author, joins us today to dive into the neuroscience behind brain health, emotional regulation, chronic pain, and supporting healthier minds across every age group.

Robin Rose, D.O., a double board-certified gastroenterologist, internal medicine specialist, and CEO of Terrain Health, joins us today to explain how lingering viral proteins from COVID can continue to affect the gut, brain, and immune system—and what we can do to identify and address their lasting impact.

Peter Attia, M.D., physician, founder of Early Medical, and expert in the applied science of longevity, joins us today to break down the key levers for extending both lifespan and healthspan—from how to train for a higher VO2 max to the biomarkers that truly predict long-term health.

Jim Murphy, a former professional baseball player turned performance coach and a #1 New York Times bestselling author, joined us today to explain how cultivating inner excellence can unlock both peak performance and deeper fulfillment in life.