No Priors: Artificial Intelligence | ...

At this moment of inflection in technology, co-hosts Elad Gil and Sarah Guo talk to the world's leading AI engineers, researchers and founders about the biggest questions: How far away is AGI? What markets are at risk for disruption? How will commerce, culture, and society change? What’s happening in state-of-the-art in research? “No Priors” is your guide to the AI revolution. Email feedback to show@no-priors.com.

Sarah Guo is a startup investor and the founder of Conviction, an investment firm purpose-built to serve intelligent software, or "Software 3.0" companies. She spent nearly a decade incubating and investing at venture firm Greylock Partners.

Elad Gil is a serial entrepreneur and a startup investor. He was co-founder of Color Health, Mixer Labs (which was acquired by Twitter). He has invested in over 40 companies now worth $1B or more each, and is also author of the High Growth Handbook.

Technology
Entrepreneurship
Science
26
What Google Cloud Can Teach Enterprises Develop...
32 min
27
From App to Suite to Platform, with HubSpot's C...
43 min
28
Model Quality, Fine Tuning & Meta Sponsoring Op...
23 min
29
If DNA is Code, Can AI Help Write It? Scaling C...
37 min
30
How Replit’s AI Tools are Changing Software Dev...
29 min
31
The Intersection of AI and Blockchain, with Tra...
42 min
32
The World’s Largest AI Processor with Cerebras ...
30 min
33
AI Superpowers for Frontend Developers, with Ve...
38 min
34
AI-Powered Biological Software with Jakob Uszko...
35 min
35
The AI Tutor For Every Child and the Next Front...
47 min
36
Listener Q&A: 2024 Tech Market Predictions, Lon...
24 min
37
Eradicating Machine Learning Pain Points with W...
43 min
38
How Palantir’s AI Bet is Revolutionizing Defens...
39 min
39
The Timeline for Realistic 4-D: Devi Parikh fro...
39 min
40
Bringing AI to the Data Cloud, with Snowflake's...
Frank Slootman, CEO of Snowflake Computing, joins Sarah Guo and Elad Gil this week on No Priors. Before scaling Snowflake to its blockbuster IPO and beyond, Frank was also the CEO from early to scale for landmark enterprise companies ServiceNow and Data Domain. Frank grew up in the Netherlands and is also the author of three books: Amp It Up, Rise of the Data Cloud, and Tape Sucks. In this episode, our hosts talk with Frank about the opportunity for generative AI in the enterprise, why Snowflake isn't really a data warehousing company, their acquisitions of Neeva and Streamlit, apps within Snowflake, and how AI relates to traditional analytics and BI. He also talks about his personal journey, why it's always a good time to do performance management, and why most leaders struggle to raise the bar for performance.
51 min
41
What's for Dinner? AI-Driven Commerce with Inst...
Fidji Simo, the CEO of Instacart and co-founder of Metrodora Institute, a research institute for neuroimmune axis disorders, shares her personal journey from growing up in France, to serving as head of product for Facebook, to becoming a wartime CEO. Fidji talks about the future of Instacart, their AI strategy, how the current era of AI is different from prior ML waves, and the impact of LLMs in commerce, robotics and healthcare. She also shares how she earns followership from her teams, leading through crisis.
39 min
42
What happens to Observability If Code is AI-Gen...
Olivier Pomel, co-founder and CEO of Datadog, the leading observability company, discusses the company’s founding story, early product sequencing, platform strategy, and acquisitions. Olivier also shares his thoughts on their more recent expansion into security, and why he’s bullish on the potential for AI in DevOps.
44 min
43
Listener Q&A: AI Misconceptions, The Reality of...
This week on No Priors, Sarah and Elad do another hangout to answer listener questions. Topics include debunking common misconceptions about AI and its implications on the world, the analogy to nuclear power and nuclear safety, the impact of larger context windows, developer productivity, incumbent announcements of AI products, and some requests for (fat) startups.
34 min
44
AI & Defense Technology with Anduril CEO Brian ...
Today on No Priors, we discuss defense technology, AI, drones, and autonomous vehicles (think giant submarine drones!) with Brian Schimpf, the co-founder and CEO of Anduril, a next-generation defense technology company. From his early days of coding at age 12 to working on self-driving cars, and finally founding Anduril, Brian's incredible journey led him to create innovative solutions for pressing defense problems. This episode covers the impact of AI, intelligent software, and other technologies to defense. We discuss the challenges of deploying and selling technology in the government spaceBrian shared his perspective on building general-purpose defense technology, the importance of a software-first approach, and how Anduril is working to solve urgent defense problems with speed and efficiency. As we wrapped up our conversation, we touched on the recent shift in the low cost of space launch, which has changed the way the US thinks about defense. We examined the proliferation of satellites, drones, and hypersonic missiles, and how these technologies can be applied, scaled, and built in a way that can fundamentally shift America's approach to defense. Don't miss this fascinating episode with Brian Schimpf as we uncover the cutting edge of defense technology and its implications for the future.
50 min
45
Going Full Send on AI, and the (Positive) Impac...
In this episode, Sarah and Elad speak with Microsoft CTO Kevin Scott about his unlikely journey from rural Virginia to becoming the driving force behind Microsoft's AI strategy. Sarah and Elad discuss the partnership that Kevin helped forge between Microsoft and OpenAI and explore the vision both companies have for the future of AI. They also discuss yesterday’s announcement of “copilots” across the Microsoft product suite, Microsoft’s GPU computing budget, the potential impact of open source AI models in the tech industry, the future of AI in relation to jobs, why Kevin is bullish on creative and physical work, and predictions for progress in AI this year.
54 min
46
The AI Will See You Now: Exploring Biomedical A...
What if AI could revolutionize healthcare with advanced language learning models? Sarah and Elad welcome Karan Singhal, Staff Software Engineer at Google Research, who specializes in medical AI and the development of MedPaLM2. On this episode, Karan emphasizes the importance of safety in medical AI applications and how language models like MedPaLM2 have the potential to augment scientific workflows and transform the standard of care. Other topics include the best workflows for AI integration, the potential impact of AI on drug discoveries, how AI can serve as a physician's assistant, and how privacy-preserving machine learning and federated learning can protect patient data, while pushing the boundaries of medical innovation.
42 min
47
Will Everyone Have a Personal AI? With Mustafa ...
Mustafa Suleyman, co-founder of DeepMind and now co-founder and CEO of Inflection AI, joins Sarah and Elad to discuss how his interests in counseling, conflict resolution, and intelligence led him to start an AI lab that pioneered deep reinforcement learning, lead applied AI and policy efforts at Google, and more recently found Inflection and launch Pi, a personalized intelligence. Mustafa offers insights on the changing structure of the web, the pressure Google faces in the age of AI personalization, predictions for model architectures, how to measure emotional intelligence in AIs, and the thinking behind Pi: the AI companion that knows you, is aligned to your interests, and provides companionship. Sarah and Elad also discuss Mustafa’s upcoming book, The Coming Wave (expected release September 12, 2023), which examines the political ramifications of AI and digital biology revolutions.
51 min
48
Personalizing AI Models with Kelvin Guu, Senior...
How do you personalize AI models? A popular school of thought in AI is to just dump all the data you need into pre-training or fine tuning. But that may be less efficient and less controllable than alternatives — using AI models as a reasoning engine against external data sources. Kelvin Guu, Senior Staff Research Scientist at Google, joins Sarah and Elad this week to talk about retrieval, memory, training data attribution and model orchestration. At Google, he led some of the first efforts to leverage pre-trained LMs and neural retrievers, with >30 launches across multiple products. He has done some of the earliest work on retrieval-augmented language models (REALM) and training LLMs to follow instructions (FLAN).
39 min
49
Listener Q&A: AI Investment Hype, Foundation Mo...
33 min
50
The Computing Platform Underlying AI, with Jens...
So much of the AI conversation today revolves around models and new applications. But this AI revolution would not be possible without one thing – GPUs, Nvidia GPUs. The Nvidia A100 is the workhorse of today’s AI ecosystem. This week on No Priors, Sarah Guo and Elad Gil sit down with Jensen Huang, the founder and CEO of NVIDIA, at their Santa Clara headquarters. Jensen co-founded the company in 1993 with a goal to create chips that accelerated graphics. Over the past thirty years, NVIDIA has gone far behind gaming and become a $674B behemoth. Jensen talks about the meaning of this broader platform shift for developers, making very long term bets in areas such as climate and biopharma, their next-gen Hopper chip, why and how NVIDIA chooses problems that are unsolvable today, and the source of his iconic leather jackets.
44 min