The two-time Emmy winner reflects on child stardom (she burst onto the scene at 14 on 'My So-Called Life'), embarking on a film career (but passing on 'Schindler's List' and 'Titanic') and returning to the small screen and experiencing career rebirth through the TV movie 'Temple Grandin,' followed by seven seasons playing a bipolar CIA officer. But first: Matthew Belloni, THR's editorial director, joins Scott to discuss a week of Hollywood wheelings and dealings: Disney and Comcast's fight over Fox, AT&T's acquisition of Time Warner and a new partnership between Oprah and Apple.

The legendary singer, songwriter, actress, writer, producer and director opens up about her odds-defying career ("I didn’t want to be a singer"), why she fights for creative control over her work ("I am not a diva") and what convinced her to embark on a rare concert tour that was later turned into a Netflix variety special — even though, as she puts it, "I just don’t enjoy singing live."

One of the few people who has played multiple iconic TV characters reflects on child stardom as a Mouseketeer, becoming "America's Sweetheart" at 21 on 'Felicity' and then, after almost quitting the biz, re-emerging as a Soviet spy for six seasons on one of the best shows of the Peak TV era.

One of the reigning kings of comedy — a standup, writer, producer and director who has been a driving force behind many of the funniest TV series and films of the last 30 years — reflects on the roots of his sense of humor, his decision to move from doing standup to writing to producing/directing and his epic documentary-tribute to one of his mentors and heroes. But first: Lesley Goldberg, THR’s west coast TV editor, joins Scott to discuss ABC's historic cancelation of 'Roseanne,' attempts to equate Roseanne Barr's and Samantha Bee's inappropriate comments and the future of 'The Walking Dead.'

One of the most talented comedy performers in the business looks back on his childhood at Nickelodeon ('All That' and 'Kenan & Kel'), losing his identity thereafter and then finding a new home in Studio 8H (where he is in his 15th season, making him the longest-tenured performer in the variety show’s history).

The star of TV’s highest-rated new network drama, whose portrayal of an autistic surgeon has already brought him a Golden Globe nom, looks back on child stardom, re-emerging as an adult on the drama series 'Bates Motel' (he received Critics' Choice noms for three of its five seasons) and then heading right into another, very different show. But first: Borys Kit, a senior staff writer at THR who oversees its 'Heat Vision' blog, joins Scott to discuss this weekend's release of 'Solo: A Star Wars Story,' this summer's roster of popcorn movies and the potential for fanboy and awards-voter overlap on 'Black Panther' and 'A Quiet Place.'

The actress-producer discusses how she wound up on '7th Heaven' at 14 (it became TV's longest-running family drama ever), growing up in the biz, making an eclectic mix of films and returning to TV in a limited series she also produced, which became 2017's most-watched new basic-cable show, and for which she received Golden Globe and Critics' Choice noms. But first: Gregg Kilday, THR's film editor, and Chris Gardner, a senior staff writer at THR, join Scott to recap the 71st Cannes Film Festival.

One of the most likable — and reliably good — actors in the business reflects on his child stardom, how he then experienced a dark decade before re-emerging as the industry’s go-to straight man in comedies and why it means so much to him to now be able to juggle acting and directing. But first: Booth Moore, THR’s Style & Fashion News Director, joins Scott to discuss the recent Met Gala, the ongoing Cannes Film Festival and the upcoming Royal Wedding, as well as Vogue's controversial new profile of Marchesa co-founder Georgina Chapman, aka Mrs. Harvey Weinstein.

The British actress, best known for playing Daenerys on TV's most acclaimed show, opens up about striking gold with and learning to navigate her first professional role, why she's sick of talking about her nude scenes, what led her to turn down 'Fifty Shades of Grey' but do 'Solo: A Star Wars Story,' plus more. But first: Stephen Galloway, THR's executive editor (features), joins Scott to discuss his recent article about Hollywood publicists and the period of upheaval currently impacting their community.

The first woman ever to host a late-night satire show reflects on her 12 years at Comedy Central's 'The Daily Show' (she was the longest-serving and first female correspondent), betting on herself by leaving that job for a show of her own at TBS (which won an Emmy in 2017) and what it's like making that show in the fast-changing and mind-blowing Trump era. But first: Seth Abramovitch, a senior writer at THR, joins Scott to discuss his new THR profile of Jeffrey Tambor, the Emmy-winning star of Amazon's'Transparent' who was recently fired from that show after being accused of sexual misconduct.

This powerhouse writer (the first black woman ever to win a comedy writing Emmy), actress ('Master of None' and 'Ready Player One') and creator/producer (Showtime's new series about Chicago's South Side) — who recently appeared on Vanity Fair's cover and was named by Time as one of the world's 100 most influential people — reflects on her upbringing, the importance of mentorship and the kaleidoscopic way her career has come together. But first: Natalie Jarvey, THR's digital media editor, joins Scott to discuss her cover story chronicling the rise of — and challenges facing — Hulu, the streaming service behind 'The Handmaid's Tale.'

The six-time Emmy nominee and two-time Critics' Choice Award winner reflects on why her agents fired her after she agreed to play Joan, how she feels about all the attention paid to her figure and why she decided to follow a period drama with a contemporary network dramedy.

The TV icon opens up about his debilitating dyslexia, overcoming it to land the part of 'The Fonz' on 'Happy Days' (and 'jumping the shark') and following 'Arrested Development' and 'Parks and Rec' with standout work on Bill Hader's new HBO dramedy. But first: David Rooney, THR's chief theatre critic, joins Scott to discuss the two-part shows that are the talk of Broadway, the return of Glenda Jackson and how the Tonys may acknowledge "The Boss."

The Golden Globe-nominated British beauty reflects on making her name in period pieces (and on 'Black Mirror'), playing one character in several projects over many years (Agent Peggy Carter of 'Captain America' fame) and the new project for which she's receiving the best reviews of her screen career (a four-part adaptation of E.M. Forster's most famous novel). But first: Rebecca Ford, THR's awards editor, joins Scott to discuss early and creative Emmy campaigning, Jimmy Kimmel vs. Sean Hannity and tough Emmy decisions facing HBO.

The model-turned-actress reflects on her big break ('Breaking Bad'), first starring role ('Don't Trust the B in Apt. 23') and experience playing a complex Marvel superhero on a Peabody Award-winning TV show that began exploring sexual misconduct and its impact on victims long before the Harvey Weinstein exposés. But first: Daniel Fienberg, THR's television critic and the president of the Television Critics Association, joins Scott to discuss what it's like to be a TV critic in the era of Peak TV, the shows you're not watching but really should be and the things about which critics and Emmy voters most and least agree.

The comic, podcast host and character actor reflects on the complex youth that led him to comedy; his rollercoaster career (he once contemplated suicide in the same garage to which a president later trekked to see him); and the Critics’ Choice and SAG award noms accorded his first major acting gig in which he's not playing a version of himself. But first: Lesley Goldberg, THR’s west coast TV editor, joins Scott to discuss the best of broadcast, pilot season and the Dodgers.

The creator, showrunner, producer, writer, director and Golden Globe-nominated star of Showtime's acclaimed new comedy series, which was largely inspired by the drama of her own experience as a young single mom, reflects on her blue-collar upbringing, accidental pregnancy at 24, move to Hollywood 11 weeks into it and years of personal and professional struggle that followed — until she took matters into her own hands by making, in 2015, a short film about her experiences that won an award at Sundance and paved the way to where she is today. But first: Michael O'Connell, THR’s senior writer on television, joins Scott to preview the 2018 Emmy season.

One of the most colorful characters in Hollywood history — he wrote, directed, produced and starred in what has been called "the 'Citizen Kane' of bad movies," which inspired 'The Disaster Artist' — opens up as never before about his life and work. But first: Matt Belloni, THR's editorial director, joins Scott to recap and dissect Sunday night's 90th Oscars.

The veteran character actor looks back on years of side-jobs and failed auditions, learning to make the most of parts of any size and landing the role of a lifetime — for which he is now favored to win the best supporting actor Oscar — in Martin McDonagh’s acclaimed dramedy. But first: Carolyn Giardina, THR’s tech editor, joins Scott to dissect — and predict — the technical Oscar categories.

Best known for his work as a director (he was half of the Merchant-Ivory team famous for its high-production-value literary adaptations), but poised to win his first Oscar for a screenplay (at 89, he'd be the oldest winner ever), he reflects on his late partner Ismail Merchant, his love of Italy and his two movies — 30 years apart — about young gay lovers. But first: Rebecca Ford, The Hollywood Reporter's awards editor, joins Scott to discuss BAFTA results, daunting stats for best picture Oscar nominees and the too-close-to-call best original song Oscar race.

One of the most recognizable and admired big screen character actors of the last 30 years reflects on decades of juggling experimental theater and films, his unconventional face and why he so often lands in edgy projects like the one for which he recently received his third Oscar nom. But first: Adam Irving, a filmmaker who received a best first documentary feature Critics' Choice Documentary Award nom for his 2016 directorial debut 'Off the Rails,' joins Scott to discuss this year's Oscar snubs of 'Jane' and 'Kedi,' doc Oscar theories of Adam Benzine and Bryan Glick and the power of Netflix in the awards sphere.

The youngest best actor Oscar nominee in 78 years — who is just 22 — reflects on the importance of his public school arts education, his early work on TV ('Homeland') and in films ('Interstellar') and the making — and crazy aftermath — of three massively acclaimed films released in 2017. But first: Roger Durling, the executive director of the Santa Barbara International Film Festival, joins Scott to discuss Santa Barbara's recovery from recent fires and mudslides, the fest's evolution during his 15 years on the job and highlights of the nominee-packed 33rd edition.

One of the top up-and-coming actresses in the business, who burst onto the scene in 2012 as Marnie on Lena Dunham’s HBO series 'Girls,' talks about emerging from her famous father's shadow, landing her breakout part despite her refusal to do on-screen nudity and holding out for years for the ideal debut film role until Jordan Peele's script came along — as a result of her starring role in NBC's 'Peter Pan Live!,' of all things — and she knew it was the one. But first: Matthew Belloni, The Hollywood Reporter's editorial director, joins Scott to discuss the nominations for the 90th Oscars, Fox Searchlight's awkward post-noms predicament, snubs of the streaming services, how #MeToo could shape the results and why we may be underestimating 'Get Out.'

The Oscar and Grammy winning composer, who has masterfully scored some 150 films, reflects on his musical influences; how he began combining instruments and technology to produce new sounds; why he nearly passed on projects for which he later produced iconic work, including 'The Lion King'; and what is at the heart of his 13-year collaboration with Christopher Nolan.

The newly-minted Golden Globe and Critics' Choice winner for best actress in a comedy series reflects on a childhood divided between acting and wrestling, her Emmy-nominated turn on Netflix's 'House of Cards' and landing the role of a lifetime — as a 1950s New York housewife-turned-standup comedian — on Amazon's new dramedy, which has resonated with women and men of all ages. But first: The Karlovy Vary International Film Festival's Krystof Mucha (executive director) and Karel Och (artistic director) join Scott to discuss the past, present and future of their annual gathering, which stands alongside Cannes, Venice and Berlin as one of Europe’s truly great film festivals.