Scientists have developed a long-sought treatment — perhaps even a cure — for sickle cell anemia. But getting it to patients might be an even bigger challenge.

And how the seemingly endless wait in the US is affecting their development.

Indiana lawyer Jim Bopp has spent most of his life chipping away at Roe v. Wade. His incremental approach to overturning the Court’s decades-old precedent appears to have paid off.

A largely unprecedented leak of a draft Supreme Court decision reveals the Court’s conservative majority intends to overturn Roe v. Wade. New York magazine’s Irin Carmon explains what that means for reproductive rights.

For less than $20 plus shipping everyday people can turn their handguns into machine guns. The Trace’s Alain Stephens explains the rise of the “auto-sear.”

Liberals turned to J.D. Vance’s book to better understand Donald Trump’s victory. Now the “Hillbilly Elegy” author is turning to Trump to try and win the Republican primary in Ohio’s Senate race.

Elon Musk and Twitter have reached a deal. Recode’s Peter Kafka and Shirin Ghaffary explain what it means for the business of Twitter, and for free speech on the platform.

Dianne Feinstein’s colleagues are concerned the 88-year-old senator is struggling with memory loss, reports Tal Kopan of the San Francisco Chronicle. It’s raising concerns about Feinstein’s ability to do her job and the aging of America's politicians.

Accounts like “Libs of TikTok” are fueling right-wing media to label people who speak openly about sexuality and gender as “groomers.” Vox’s Aja Romano and the Washington Post’s Taylor Lorenz explain this age-old practice.

By making bitcoin a national currency, El Salvador tried to transform its economy. Rest of World’s Leo Schwartz explains why the bet hasn’t yet paid off.

A Florida judge ended the federal government’s mass transit mask mandate this week. Vox’s Dylan Scott explains if mask mandates are over forever and Dr. Kavita Patel explores how much of a difference that would make.

The Wagner Group, a superviolent (and supersecretive) team of Kremlin-aligned mercenaries, is doing Vladimir Putin’s dirty work in Ukraine and around the world.

Elon Musk says he wants to buy Twitter, but is also making 420 jokes. Kara Swisher (who knows him) and Liz Lopatto (who doesn’t) explain whether the world should take him seriously (or care).

Last year, Vox correspondent Dylan Matthews didn’t think inflation would be a big deal. He wasn’t the only one to miss the mark.

Russia is ramping up attacks on Ukraine’s digital infrastructure. The US could be next.

Warner Bros. is censoring the newest Fantastic Beasts movie for Chinese audiences. It’s the latest reminder that Hollywood’s reliance on China comes at a cost.

The congressional committee investigating the Capitol insurrection has gathered an enormous amount of information. Now it must decide what to do with it. Politico’s Kyle Cheney explains five crucial decisions that remain.This episode was produced by Miles Bryan, edited by Matt Collette, engineered by Paul Mounsey, fact-checked by Laura Bullard, and hosted by Sean Rameswaram.

Hunter Biden may not be the archcriminal that conservatives describe, but his actions present problems for his father (the president of the United States). Vox's Andrew Prokop explains.

Pakistan’s prime minister was ousted. He blames the US.

Starting a union can be a tall order, but many baristas have found it’s an effective way to venti their frustration with management.

Vladimir Putin says the West is trying to erase 1,000 years of culture. Arts organizations say they have an obligation to respond to the war in Ukraine.

The Buffalo Bills are set to receive $850 million in public funds to build a new stadium — even though they’re owned by a fracking billionaire and weren’t threatening to leave. An economist explains whether publicly funded stadiums ever work out in the public’s favor.

A 2012 law tried to limit lawmakers' ability to make money on Wall Street. It hasn’t worked.

The Russian president has come to rely on a skewed version of history and an increasingly small circle of advisers. Journalist Marvin Kalb explains what that means for the war in Ukraine.

A groundbreaking new study claims to have found a way for a fully paralyzed person to communicate entirely via thought. But the scientists behind it have a checkered past.